Farm Talk

Equine

June 18, 2013

Stem cell therapy gives new life to ailing horses

Parsons, Kansas — There is potential for a revitalized life of once elite performance horses stricken by injury and other disabling conditions.

Adult stem cells, which have the ability to differentiate into almost any type of cell, have offered development of medical treatments for a wide range of illness and incapacitating conditions in humans.

“Currently, adult stem cells are also being used to treat animals with a variety of illness and injuries with very encouraging, if not amazing, results,” said Dr. Larry Snyder, veterinarian at the University Bird and Small Animal Clinic in Topeka.

On the ground floor of incorporating the use of adult stem cells in animal treatment, Snyder has worked closely with other veterinarians throughout the Midwest including Dr. Preston Hickman, veterinarian at Wichita Equine & Sports Medicine.

“I had used various types of stem cells before, with very little to limited success, so I was at first hesitant when Larry (Snyder) suggested I try stem cell treatment on a former upper level dressage horse that had been severely injured while grazing in the pasture,” Hickman said.

The 14-year-old Dutch Warmblood-Thoroughbred cross mare had already been retired from competitions due to an unrelated debilitating injury, considered permanent by the then owner-trainer.

“However, Larry was persistent insisting that this new fifth generation technology was entirely different. After several phone calls, I agreed to try it on the mare named Zoe,” Hickman said.

Owners Judy and Jim Baxter, were concerned about the costs, it was decided to attempt stem cell treatment on the fracture to the right forefoot and torn suspensory ligament.

“Zoe received the first fifth-generation stem cells in this part of the Midwest, and made rapid recovery,” Hickman said.

Prior to retirement, the mare had been shown in upper level dressage, but was forced from competitions due to a torn ligament in the same leg, despite considerable and diverse treatment efforts of several top equine veterinarians and farriers.

“By day 45, following stem cell therapy, Zoe had progressed to the point that we put her back to work under saddle. She seemingly retained her earlier championship-quality training prowess. This caused her previous owner-trainer bittersweet pleasure, wishing she’d been able to complete the treatments much earlier,” Hickman said.

“I have radiographed her fetlock and am astounded that the fracture line is almost completely resolved, and there is no evidence of pain in the ankle. I am still stunned at this mare’s progress,” he added.

“Therapy with stem cells from the animal being treated is proving to be one of the safest methods of treatment present today,” Snyder stated.

“The cells are from the animal’s own fat and are recognized by the body’s immune system as ‘self,’ and therefore well tolerated. When applied properly, the stem cells cause no damage, and have an amazing property to reduce, or stop inflammation, and initiate healing of the damage naturally,” he said.

Most pharmaceutical products cause adverse conditions, often more severe than the ailment. “With stem cell therapy, we see no adverse reactions, but rather typically improved mental function, reduced anxiety and improved skin condition,” Snyder added.

More than 20 equine cases, ranging from arthritis to several types of fractures and ligament damage, have now been treated with stem cell therapy by Hickman.

“I am amazed that all of these cases have responded, although some more than others. But, indeed everyone has benefited from this technology,” Hickman said.

Snyder pointed out that he and Hickman are currently conducting a research project using stem cells on chronic laminitis, or ‘founder,’ in horses.

“Preliminary results have been extremely encouraging in promoting re-establishment of blood flow to the hoof wall and potentially allowing the hoof to ‘heal,’ rather than continued progression and pain of the classic foundered horse,” Snyder said.

(continued from page 14)

Besides horses, Snyder has been successful with stem cell treatment of dogs and other animals.

“We have even treated arthritis in a Red Kangaroo at Rolling Hills Zoo in Salina. The joint was severely injured for eight months before being treated with stem cells. Zoo personnel now report considerable improved movement and comfort in the kangaroo,” Snyder said.

Stem cells are being used around the world in humans and animals to treat and heal arthritis, accelerate fracture healing, repair intervertebral disk damage, reverse and heal lesions of Alzheimer’s disease, stabilize immune diseases and minimize and heal damage from heart attack, the veterinarians explained.

“I truly am astonished at the progress of the ailing horses treated with this new technology. This truly is the greatest modality I have ever had the opportunity to use in my practice,” Hickman contended.

“Regenerative medicine and stem cell use in general is the future of medicine in both humans and all animals. Using the body to ‘heal itself’ is the essence of naturopathic medical concept and will become more and more the normal for healing in medicine of all species,” Snyder said.

According to him, “We always try to emphasis that the stem cells that we are using are from the animal being treated and are from that animal’s’ own fat. Embryonic stem cells may serve in future research, but have so far been a failure in treating any condition in either animals or humans.”

It was also noted that there is effort to conduct studies at Kansas State University on use of adult stem cells for treatment of arthritis in dogs. “We’re working to get research in high gear within the Kansas Bio Corridor, with more species being involved as the research progresses,” Snyder added.

Best proof is in the end results as Zoe was ridden by Bekki Moore in the Kansas Dressage & Eventing Association competition in Hutchinson the first weekend of the month.

“She placed first in three classes, third in another one and was second overall,” related Dr. Snyder, who was there along with Dr. Hickman watching the performance in third and fourth level dressage competition.

“She did not have a painful step during the entire time. All of the people involved with Zoe are amazed with this complete healing. Zoe even gave Dr. Hickman a ‘hug’ after the competition, a very moving gesture from a beautiful animal. We are all very impressed with this treatment and happy for Zoe and her owners and trainers,” Snyder concluded. £

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